Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-09-06
2005-09-06
Rao, Deepak (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S324000
Reexamination Certificate
active
06939874
ABSTRACT:
The invention encompasses compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions, uses and methods for prophylaxis and treatment of cancer.
REFERENCES:
patent: 2585910 (1952-02-01), Barton et al.
patent: 2585972 (1952-02-01), Stacey et al.
patent: 2585979 (1952-02-01), Vasey
patent: 2643253 (1953-06-01), Curd et al.
patent: 4983608 (1991-01-01), Effland et al.
patent: 5043317 (1991-08-01), Chapman et al.
patent: 5935966 (1999-08-01), Suto et al.
patent: 5958935 (1999-09-01), Davis et al.
patent: 6080858 (2000-06-01), Schumacher
patent: 0 379 806 (1996-04-01), None
patent: 0 945 443 (1999-09-01), None
patent: 1 040 831 (2000-10-01), None
patent: 794043 (1958-04-01), None
patent: WO 94/26733 (1994-11-01), None
patent: WO 95/33750 (1995-12-01), None
patent: WO 97/19065 (1997-05-01), None
patent: WO 98/41512 (1998-09-01), None
patent: WO 99/31073 (1999-06-01), None
patent: WO 99/41253 (1999-08-01), None
patent: WO 99/50250 (1999-10-01), None
patent: WO 00/27825 (2000-05-01), None
patent: WO 00/39101 (2000-07-01), None
patent: WO 00/53595 (2000-09-01), None
patent: WO 00/59892 (2000-10-01), None
patent: WO 00/78731 (2000-12-01), None
patent: WO 01/00213 (2001-01-01), None
patent: WO 01/19825 (2001-03-01), None
patent: WO 01/22938 (2001-04-01), None
patent: WO 01/29009 (2001-04-01), None
patent: WO 01/40218 (2001-06-01), None
patent: WO 01/47921 (2001-07-01), None
patent: WO 01/55116 (2001-08-01), None
patent: WO 01/60816 (2001-08-01), None
patent: WO 01/72717 (2001-10-01), None
patent: WO 01/72745 (2001-10-01), None
patent: WO 01/85700 (2001-11-01), None
patent: WO 02/22601 (2002-03-01), None
patent: WO 02/46170 (2002-06-01), None
patent: WO 02/46171 (2002-06-01), None
patent: WO 02/46184 (2002-06-01), None
patent: WO 02/47690 (2002-06-01), None
patent: WO 02/48147 (2002-06-01), None
patent: WO 02/48148 (2002-06-01), None
patent: WO 02/50065 (2002-06-01), None
patent: WO 02/50066 (2002-06-01), None
patent: WO 02/057259 (2002-07-01), None
patent: WO 02/059110 (2002-08-01), None
Girnita et al., Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor, PNAS, vol. 100, No. 14, pp. 8247-8252, 2003.
Romano, The complex biology of the Receptor for the Insulin-like Growth Factor-1, Drug News & Perspectives, Abstract, vol. 16, No. 8, Oct. 2003.
Khandwala et al., The Effects of Insulin-like Growth Factors on Tumorigenesis and Neoplastic Growth, Endocrine Reviews, 21 (3), pp. 215-244, 2000.
Ellis et al., Insulin-like Growth Factors in human breast cancer, Breast Cancer Research and Treatment 52:175-184, 1998.
Traxler, Review: Oncologic, Endocrine & Metabolic, Protein tyrosine kinase inhibitors in cancer treatment, Exp. Opin. Ther. Patents, 7(6), pp. 571-588, 1997.
Simone, Oncology: Introduction,Cecil Textbook of Medicine, 20th Edition, vol. 1, pp. 1004-1010, 1996.
Ghoneim et al., “Synthesis and Evaluation of Some 2-, 4-, and 2,4-Disubstituted-6-Methylpyrimidine Derivatives for Antimicrobial Activity” (1978) 28: 117-126.
Buchanan John L.
Chaffee Stuart
Harmange Jean-Christophe
Novak Perry M.
Van Der Plas Simon
Amgen Inc.
Bulock Joseph W.
Rao Deepak
LandOfFree
Substituted pyrimidinyl derivatives and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted pyrimidinyl derivatives and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted pyrimidinyl derivatives and methods of use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3394119