Substituted pyrido-triazines as anthelmintics

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260248NS, C07D25172

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active

039845494

ABSTRACT:
Pyrido-(1,2-a)-1,3,5-triazines which are variously substituted on the triazine ring at the 3-position and on the pyridine ring on any of the available positions are active anthelmintic and antifungal agents and are prepared by condensing a substituted isocyanate or an isothiocyanate with a pyridyl-isocyanate or isothiocyanate. The compounds are disclosed in compositions and methods for the treatment of helminthiasis and fungal diseases.

REFERENCES:
patent: 3609148 (1971-09-01), Hoegerle et al.
patent: 3835145 (1974-09-01), Dickinson et al.
Blatter et al., Tetrahedron Letters, No. 18, pp. 1087-1091, (1964).
Howard et al., J. of Organic Chemistry, vol. 25, pp. 829-832, (1960).
Fairfull et al., Jour. Chem. Soc., pp. 796-802, (1955).

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