Substituted pyrido[2,3-d]pyrimidines and methods for their use

Details Substituted pyrido[2,3-d]pyrimidines and methods for their use Substituted pyrido[2,3-d]pyrimidines and methods for their use

2005-11-15

2005-11-15

McKenzie, Thomas (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S279000

Reexamination Certificate

active

06964967

ABSTRACT:
Compounds having the formula:wherein A4is N and X is —C(O)— or —CH2—, are provided, which are useful as modulators of a chemokine receptor and for treatment of inflammatory and immunoregulatory disorders and diseases. Pharmaceutical compositions and methods of using these compounds for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis and type I diabetes, are also provided.

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