Substituted pyrido (1,2-c)imidazo(1,2-a)benzimidazoles, processe

Details Substituted pyrido (1,2-c)imidazo(1,2-a)benzimidazoles, processe Substituted pyrido (1,2-c)imidazo(1,2-a)benzimidazoles, processe

1984-09-13

1986-04-29

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 64, 546278, 546296, A61K 3144, C07D47112

Patent

active

045857750

ABSTRACT:
The invention relates to compounds of the formula ##STR1## in which R.sup.1 and R.sup.2 are identical or different and are hydrogen, alkyl, trifluoromethyl, halogen, alkoxycarbonyl, alkoxy or alkanoyl, R.sup.3, R.sup.4 and R.sup.5 are identical or different and are hydrogen, methyl, alkoxy or alkoxyethoxy, and R is hydrogen or a group SR.sup.6, in which R.sup.6 is the lone, unpaired electron of the 12-sulfenyl radical, hydrogen, optionally substituted alkyl, alkenyl, alkynyl, alkanoyl, optionally mono- or poly-substituted benzoyl, fuoryl, phenacyl, phenoxyacetyl, phenylacetyl or another conventional thiol-protective group, and to physiologically acceptable salts thereof, and to processes for their preparation, to their use as a gastric acid secretion inhibitor and to pharmaceutical preparations based on these compounds.

REFERENCES:
patent: 3880866 (1975-04-01), Herbst et al.
patent: 3880870 (1975-04-01), Ledig et al.
patent: 3911130 (1975-10-01), Herbst et al.
patent: 4254127 (1981-03-01), Vandenberk et al.
patent: 4255573 (1981-03-01), Adhikary
patent: 4472409 (1984-09-01), Senn-Bilfinger
Irikura et al., Chemical Abstracts, vol. 78, 4251r, 1973.
Brimblecombe et al., Proceedings of the B.P.S., 1/8/75-1/10/75, pp. 435P-436P.

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