Substituted pyrido[1,2,3,-de]-1,4-benzoxazines as bactericides

Details Substituted pyrido[1,2,3,-de]-1,4-benzoxazines as bactericides Substituted pyrido[1,2,3,-de]-1,4-benzoxazines as bactericides

1974-11-21

1976-10-05

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 31535, A61L 1300

Patent

active

039845486

ABSTRACT:
Anti-microbial agents which are 2,3-dihydro-3-substituted-7-oxo-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxy lic acids are prepared by condensation of benzoxazines with ethoxymethylene malonate esters followed by ring closure with poly phosphoric acid and hydrolysis of the resulting esters.

REFERENCES:
patent: 3055894 (1962-09-01), Lombardino et al.
patent: 3551565 (1970-12-01), Clarke
Chem. Abst. 72 90686(s) (1970), Teacher et al.

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