Substituted pyridinones

Details Substituted pyridinones Substituted pyridinones

2006-06-27

2006-06-27

Davis, Zinna Northington (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S256000, C514S336000, C546S283400, C546S296000, C544S333000

Reexamination Certificate

active

07067540

ABSTRACT:
Disclosed are compounds Formula Iand pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.

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