Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-06-25
1994-10-18
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514332, 514336, 514343, 514350, 514352, 546261, 546262, 546263, 546281, 546283, 546284, 546299, 546309, 546310, C07D21381, A61K 3144
Patent
active
053569091
ABSTRACT:
The invention relates to substituted pyridine-2,4-dicarboxylic acid derivatives of the formula I ##STR1## in which R.sup.1 and R.sup.2 have the meanings given. The invention also relates to a process for the preparation of the abovementioned compounds and to their use as medicaments, in particular as fibrosuppressants and immunosuppressants.
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Heinisch et al., Heterocycles, vol. 26, No. 3, pp. 731-744 (1987).
Beilsteins Handbuch der Organischen Chemie, 4, Auflage, drittes und viertes Erganzungswerk, vol. 20, pp. 1655 and 1778 (1979).
Gunzler et al., Collagen and Rel. Research, vol. 3, p. 71 (1983).
Majamaa et al., Eur. J. Biochem., vol. 138, pp. 239-245 (1984).
Sugiyama et al., Bull. Chem. Soc. Japan, vol. 58, No. 4, pp. 1331-32 (1985).
Jones, J.A.C.S., vol. 73, pp. 5610-14 (1951).
Baader Ekkehard
Bickel Martin
Brocks Dietrich
Gunzler Volkmar
Hanauske-Abel Hartmut
Davis Zinna N.
Hoechst Aktiengesellschaft
Ivy C. Warren
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