Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-06-07
2005-06-07
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S252030, C544S237000, C544S238000
Reexamination Certificate
active
06903101
ABSTRACT:
Substituted and Fused pyridazines having angiogenesis inhibiting activity and the generalized structural formulawherein the ring containing A, B, D, E, and L is a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; R1and R2may be defined independent substituents or together may be a ring-defining bridge; ring J may be an aryl, pyridyl, or cycloalkyl group; and G groups may be any of a variety of defined substituents. Pharmaceutical compositions containing these materials, and methods of treating a mammal having a condition characterized by abnormal angiogenesis or hyperpermiability processes using these materials are also disclosed.
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Chemical Abstract: 115:256197; Uenishi, Keiji; Kosegi,Koji; Asaumi, Yoshio; Ishizuka, Yasuhiro; Yaginuma, Hideya; “Preparations of 1-(3-pyridylmethyl)phthalazines as blood platelet aggregation inhibitors”, Jpn.Kokai Tokkyo Koho, 6 pp.
Boyer Stephen James
Dumas Jacques P.
Hatoum-Mokdad Holia N.
Joe Teddy Kite
Kluender Harold C. E.
Balasubramanian Venkataraman
Bayer Pharmaceuticals Corporation
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