Substituted pyrazolopyrimidines and thiazolopyrimidines

Details Substituted pyrazolopyrimidines and thiazolopyrimidines Substituted pyrazolopyrimidines and thiazolopyrimidines

2006-11-14

2006-11-14

McKenzie, Thomas C. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C544S278000, C544S281000, C514S259200, C514S259300, C514S267000

Reexamination Certificate

active

07135568

ABSTRACT:
Substituted pyrazolopyrimidines and thiazolopyrimidines, specifically, compounds corresponding to the structure (I A), (I B) or (II)processes for their preparation, substance libraries containing them, pharmaceutical formulations containing these compounds, the use of these compounds for the production of medicaments for the treatment and/or prophylaxis of pain and related treatment methods are provided.

REFERENCES:
patent: 10112197 (2002-09-01), None
patent: WO-02/027585 (2002-09-01), None
Mobius HJ. Int J Geriatr Psychiatry. Sep. 2003;18(Suppl 1):S47-54.
Lee KR et al, Cerebrovasc Dis. 2001;11(1):20-9, Medline abstract PMID: 11173790.
Low SJ, Roland CL., Int J Clin Pharmacol Ther. Jan. 2004;42(1):1-14, Medline abstract PMID: 14756381.
Walters MR, Bradford AP, Fischer J, Lees KR., Br J Clin Pharmacol. Mar. 2002;53(3):305-11.
West, Anthony R., Solid State Chemistry and its Applications, Wiley, New York, 1988, pp. 358 & 365.
Coleman, Robert A, “Medicinal Chemistry: Principles and Practice, Chapter 4, Frank D. King ed.”, The Royal Society of Chemistry, Cambridge, 1994, pp. 53-58.
David J.W. Grant, “University of Minnesota—Twin Cities Campus College of Pharmacy, Annual Report”, [online] 1999, [retrieved on Feb. 13, 2003]. Retrieved from the internet, <http://www.msi.umn.edu/general/Reports/ar99/departments/pharmacy.html>.
Vippagunta, S. R. et al, Advanced Drug Delivery Reviews, 48, 3-26, 2001.
P. Leeson et al. “The Glycine Site on the NMDA Receptor: Structure-Activity Relationships and Therapeutic Potential”J. Med. Chem.37(24):4053-4067.
P. Krogsgaard-Larsen et al. “Design of Excitatory Amino Acid Receptor Agonists, Partial Agonists and Antagonists: Ibotenic Acid as a Key Lead Structure”Eur. J. Med. Chem.(1996) 31:515-537.

Affiliated with

Also associated with

Rating

Substituted pyrazolopyrimidines and thiazolopyrimidines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted pyrazolopyrimidines and thiazolopyrimidines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted pyrazolopyrimidines and thiazolopyrimidines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3652367