Substituted pyrazolo[3,4-d]pyrimidines as p38 MAP kinase...

Details Substituted pyrazolo[3,4-d]pyrimidines as p38 MAP kinase... Substituted pyrazolo[3,4-d]pyrimidines as p38 MAP kinase...

2006-08-23

2009-10-13

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S262000, C544S350000, C514S249000, C514S303000, C546S119000

Reexamination Certificate

active

07601726

ABSTRACT:
Compounds of formula Ia or Ib:wherein A, W, X, Y, R1, R2, R3and R4are as defined herein. Also disclosed are methods of making the compounds and methods of using the compounds for treatment of p38 MAP kinase-mediated diseases.

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Gong, P. et. al., “Synthesis and Vasodilatory Activities of New Pyrazolo [3,4-d] pyrimidin-4-one Derivatives,”Chinese Chemical Lettersvol. 13, No. 7 (2002) pp. 613-616.

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