Substituted pyrazolo [3,4-d]pyrimidines as cytokine modulators

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C544S262000

Reexamination Certificate

active

07569571

ABSTRACT:
Provided are bicyclic heterocycle-based p38 kinase, including p38α and p38β kinase, inhibitors. Pharmaceutical compositions containing the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.

REFERENCES:
patent: 6005109 (1999-12-01), Faraci et al.
patent: WO03/097062 (2003-11-01), None
patent: WO03/099820 (2003-12-01), None
STN search downloaded Feb. 16, 2008.

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