Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-05-24
2011-05-24
Moore, Susanna (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S262000
Reexamination Certificate
active
07947694
ABSTRACT:
This invention comprises the novel compounds of formula (I)wherein R1, R2, R3, R4, R5, R6, X1and X2have defined meanings, having cell cycle kinase inhibiting enzymatic activity, their preparation, compositions containing them and their use as a medicine.
REFERENCES:
patent: 6552192 (2003-04-01), Hanus et al.
patent: 2004/0248905 (2004-12-01), Markwalder et al.
patent: 153976 (1985-09-01), None
patent: WO 98/16184 (1998-04-01), None
patent: WO 00/43394 (2000-07-01), None
patent: WO 01/49688 (2001-07-01), None
patent: WO 03/063764 (2003-08-01), None
patent: WO 03/099820 (2003-12-01), None
patent: WO 2004/065378 (2004-08-01), None
patent: WO 2004/094426 (2004-11-01), None
patent: WO 2006/074984 (2006-07-01), None
Mahadevan et. al. (Expert Opinion, 2007, pp. 1011-1026).
Fischer et. al. (Expert Opin. Investig. Drugs, 2005, pp. 457-477).
Strecker et. Al. (Expert Opin. Emerging Drugs, 2008, pp. 573-591).
Fischer, P.M., et al., “CDK inhibitors in clinical development for the treatment of cancer”, Expert Opin. Investig. Drugs, vol. 12, No. 6 (2003), pp. 955-970.
McLaughlin, F., et al., “The cell cycle, chromatin and cancer: mechanism-based therapeutics come of age”, Drug Discovery Today, vol. 8, No. 17 (2003), pp. 793-802.
International Search Report PCT/EP2006/050096, mailed May 4, 2006.
Freyne Eddy Jean Edgard
Lacrampe Jean Fernand Armand
Lardeau Delphine Yvonne Raymonde
Lavrijssen Tom
Ligny Yannick Aimé Eddy
Janssen Pharmaceutica NV
Moore Susanna
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