Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-05-14
2010-12-14
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S234200, C514S252160, C514S262100, C514S261100, C514S258100, C514S266200, C514S264100, C514S264110, C544S058200, C544S061000, C544S118000, C544S262000, C544S254000, C544S245000, C544S279000
Reexamination Certificate
active
07851468
ABSTRACT:
The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted heterobicyclic pyrimidines of Formula (I):wherein R1, R2, R3, R4, R5, X, W, and ring A are as defined herein; pharmaceutical compositions of substituted heterobicyclic pyrimidines of Formula (I); and their use in the treatment of chronic neurodegenerative diseases, neurotraumatic diseases, depression and/or diabetes. More particularly, the present invention relates to substituted pyrazolopyrimidines of Formula (I).
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Wolff, Manfred E. “Burger's Medicinal Chemistry, 5ed, Part I”, John Wiley & Sons, 1995, pp. 975-977.
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Chu, Ih et al.,Journal of Medicinal Chemistry, Synthesis and Biological Evaluation of Xanthine Oxidase Inhibitors, Pyrazolo[3,4-d]pyrimidines and Pyrazolo[3,4-b]pyridines, 1975, 18(2), 161-165.
Bacon Edward R.
Bailey Thomas
Becknell Nadine C.
Gingrich Diane E.
Hostetler Greg
Cephalon Inc.
Moore Susanna
Wilson James O
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