Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase...

Details Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase... Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase...

2003-12-05

2009-06-23

Coleman, Brenda L (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S281000

Reexamination Certificate

active

07550470

ABSTRACT:
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, macular edema, retinal ischemia, inflammatory diseases, and the like in mammals.

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