Substituted pyrazinone amides useful for activation of...

Details Substituted pyrazinone amides useful for activation of... Substituted pyrazinone amides useful for activation of...

2010-01-20

2011-12-06

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S406000, C546S268100, C549S356000

Reexamination Certificate

active

08071606

ABSTRACT:
The present invention provides compounds of Formula (I)that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. The variables R1, R2, R3and R4are as described herein.

REFERENCES:
patent: 2003/0139402 (2003-07-01), Konradi et al.
patent: 2004/0147512 (2004-07-01), Konradi et al.
patent: 2006/0058353 (2006-03-01), Mckerrecher et al.
patent: 2007/0213349 (2007-09-01), Cheruvallath et al.
patent: 1 433 778 (2004-06-01), None
patent: 2006-177436 (2006-07-01), None
patent: WO 93/04580 (1993-03-01), None
patent: WO 96/10016 (1996-04-01), None
patent: WO 97/28133 (1997-08-01), None
patent: WO 00/66557 (2000-11-01), None
patent: WO 02/20463 (2002-03-01), None
patent: WO 02/40448 (2002-05-01), None
patent: WO 02/051836 (2002-07-01), None
patent: WO 03/068230 (2003-08-01), None
patent: WO 03/092670 (2003-11-01), None
patent: WO 2004072066 (2004-08-01), None
patent: WO 2005/018557 (2005-03-01), None
patent: WO 2006/015159 (2006-02-01), None
patent: WO 2006/028833 (2006-03-01), None
patent: WO 2006/098683 (2006-09-01), None
patent: WO 2007/026761 (2007-03-01), None
patent: WO 2007043638 (2007-04-01), None
patent: WO 2007/058580 (2007-05-01), None
patent: WO 2007117995 (2007-10-01), None
patent: WO 2008079787 (2008-07-01), None
Sarabu et al, Expert Opinion on Therapeutic Patents, vol. 18, No. 7, pp. 759-768, 2008.
R. Krause et al., Amino Acids, vol. 27, No. 1, pp. 9-18, 2004.
Moller, Nature 414, pp. 821-827, 2001.

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