Substituted pyrazines, pyrimidines and pyridazines for use in th

Details Substituted pyrazines, pyrimidines and pyridazines for use in th Substituted pyrazines, pyrimidines and pyridazines for use in th

1991-12-17

1993-06-15

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514254, 514256, 514269, 514913, 540582, 544238, 544239, 544333, 544298, 544405, A61K 3155, A61K 31495, C07D22300, C07D29500, C07D23700, C07D40100

Patent

active

052198499

ABSTRACT:
A class of pyrazine, pyrimidine and pyridazine derivatives, substituted by a non-aromatic azabicyclic ring system and optionally by up to two further substituents, is of use in the preparation of medicaments, especially formulations adapted for topical administration to the eye, suitable for the treatment of glaucoma and/or for reducing intraocular pressure.

REFERENCES:
Drugs, 1979, vol. 17, 38.
Drugs, and Ther., Bull., 1989, vol. 21, 85.

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