Substituted propane-phosphonuous acid compounds

Details Substituted propane-phosphonuous acid compounds Substituted propane-phosphonuous acid compounds

1986-12-12

1988-09-20

Evans, J. E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

C07F 948, A61K 3104

Patent

active

047727381

ABSTRACT:
The compounds of the formula ##STR1## in which one of the groups R.sup.1, R.sup.2 and R.sup.3 represents hydrogen, C.sub.1-8 -alkyl, C.sub.3-6 -cycloalkyl, phenyl optionally substituted by halogeno, C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy and/or trifluoromethyl, or C.sub.7-10 -phenylalkyl optionally substituted in the phenyl moiety by halogeno, C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy and/or trifluormethyl, and the other two are hydrogen, or salts thereof.
These compounds have valuable pharmaceutical properties.

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Krevtzkamr et al., "Chem. Abstracts", vol. 57 (1962), columns 5946 and 5947.
Enna, et al., J. Med. Chem. 27, pp. 654-659, (1984).
Aust. J. Chem. 33, pp. 287-294, (1980).

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