Substituted propane-phosphonous acid compounds

Details Substituted propane-phosphonous acid compounds Substituted propane-phosphonous acid compounds

1985-10-15

1987-04-07

Evans, J. E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

2605025R, 514114, C07F 708, C07F 948, A61K 3113, A61K 31185

Patent

active

046562982

ABSTRACT:
The compounds of the formula ##STR1## in which one of the groups R.sup.1, R.sup.2 and R.sup.3 represents hydrogen, C.sub.1-8 -alkyl, C.sub.3-6 -cycloalkyl, phenyl optionally substituted by halogeno, C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy and/or trifluoromethyl, or C.sub.7-10 -phenylalkyl optionally substituted in the phenyl moiety by halogeno, C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy and/or trifluormethyl, and the other two are hydrogen, or salts thereof.
These compounds have valuable pharmaceutical properties.

REFERENCES:
patent: 3374288 (1968-03-01), Lange
patent: 3385822 (1968-05-01), Brown
patent: 4386013 (1983-05-01), Callahan et al.
patent: 4390690 (1983-06-01), DiGiacomo et al.
Enna, et al., J. Med. Chem. 27, 654 (1984).
Aust. J. Chem. 33, 292 (1980).
J. Med. Chem. 27, 654-659 (1984).
Aust. J. Chem. 33, 287-294 (1980).
English Abstract of Russian Pat. No. 1174439 published 8/28/85.

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