Substituted prolinamides, manufacturing, and the use thereof...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S314000, C514S422000, C546S159000, C546S162000, C546S165000, C548S518000

Reexamination Certificate

active

07807693

ABSTRACT:
The present invention relates to new substituted prolinamides of general formula (I)wherein D, L, E, G, J, M, R3, R4, R5and R13are defined as in the specification, the tautomers, the enantiomers, the diastereomers, the mixtures, and the salts thereof.

REFERENCES:
patent: 2007/0015812 (2007-01-01), Boehringer et al.
patent: 2 520 893 (2004-10-01), None
patent: 2 521 069 (2004-10-01), None
patent: 2 529 453 (2004-12-01), None
patent: 2 549 589 (2005-06-01), None
patent: 2 561 057 (2005-10-01), None
patent: 2 581 172 (2006-03-01), None
patent: 03/045912 (2003-06-01), None
patent: 2004/087646 (2004-10-01), None
patent: 2004/087695 (2004-10-01), None
patent: 2004/110433 (2004-12-01), None
patent: WO 2004110433 (2004-12-01), None
patent: 2005/058817 (2005-06-01), None
patent: 2005/092849 (2005-10-01), None
patent: 2006/032342 (2006-03-01), None
patent: 2006/108709 (2006-10-01), None
George J. Qualich, et al; Synthesis of 1,2,3,4-Thetrahydroisoquinolines Containing Electron-Withdrawing Groups; Journal of Organic Chemistry (1998) vol. 63 pp. 4116-4119.
Molina Mhatre, et al; Thrombin, a Mediator of Neurotoxicity and Memory Impairment; Neurobiology of Aging (2004) vol. 25 pp. 783-793.
Haruhiko Akiyama, et al; Thrombin Accumulation in Brain of Patients with Alzheimer's Disease; Neuroscience Letters (1992) vol. 146 pp. 152-154.
Sang-H. Choi, et al; Thrombin-Induced Microglial Activation Produces Degeneration of Nigral Dopaminergic Neurons in Vivo; The Journal of Neuroscience (2003) vol. 23 No. 13 pp. 5877-5886.
International Search Report for PCT/EP2007/054631 mailed Nov. 14, 2007.
Jag P. Heer et al; Preparation of 1,7-Disubstituted-1,2,3,4-Tetrahydroisoquinolines; Synthetic Communications (2002) vol. 32 No. 16 pp. 2555-2563.
John D. Harling, et al; A Facile Synthesis of the 3-Amino-5,6,7,8-Tetrahydro[1,6]Naphthyridine System and Some Alkylated and Polycyclic Homologues; Synthetic Communications (2001) vol. 31 No. 5 pp. 787-797.
Simone Durand-Henchoz, et al; No. 585.—Nitration of 2-Methyl-1,2,3,4-Tetrahydroisoquinoline; Bulletin of the French Chemical Society (1966) vol. 11, pp. 3413-3416.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Substituted prolinamides, manufacturing, and the use thereof... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted prolinamides, manufacturing, and the use thereof..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted prolinamides, manufacturing, and the use thereof... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4185700

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.