Substituted porphyrins

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S410000, C540S145000

Reexamination Certificate

active

07820644

ABSTRACT:
The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.

REFERENCES:
patent: 2951799 (1960-09-01), Sharp
patent: 4614723 (1986-09-01), Schmidt
patent: 4657902 (1987-04-01), Kappas et al.
patent: 4746735 (1988-05-01), Kruper, Jr. et al.
patent: 4758422 (1988-07-01), Quay
patent: 4837221 (1989-06-01), Bonnett
patent: 4851403 (1989-07-01), Picker et al.
patent: 4885114 (1989-12-01), Gordon et al.
patent: 4892941 (1990-01-01), Dolphin et al.
patent: 4895719 (1990-01-01), Radhakrishnam
patent: 4963367 (1990-10-01), Ecanow
patent: 5051337 (1991-09-01), Sakoda et al.
patent: 5130245 (1992-07-01), Marklund et al.
patent: 5162519 (1992-11-01), Bonnett
patent: 5169630 (1992-12-01), Okaya et al.
patent: 5171680 (1992-12-01), Mullenbach et al.
patent: 5192757 (1993-03-01), Johnson et al.
patent: 5202317 (1993-04-01), Bruice
patent: 5217966 (1993-06-01), Bruice
patent: 5223538 (1993-06-01), Fridovich
patent: 5227405 (1993-07-01), Fridovich
patent: 5236914 (1993-08-01), Meunier
patent: 5236915 (1993-08-01), Fiel
patent: 5248603 (1993-09-01), Marklund et al.
patent: 5262532 (1993-11-01), Tweedle et al.
patent: 5281616 (1994-01-01), Dixon et al.
patent: 5284647 (1994-02-01), Niedballa et al.
patent: 5366729 (1994-11-01), Marklund et al.
patent: 5472691 (1995-12-01), Marklund et al.
patent: 5493017 (1996-02-01), Thieren et al.
patent: 5599924 (1997-02-01), Therien et al.
patent: 5674467 (1997-10-01), Maier et al.
patent: 5747026 (1998-05-01), Crapo
patent: 5767272 (1998-06-01), Wijesekera et al.
patent: 5834509 (1998-11-01), Malfroy-Camine et al.
patent: 5948771 (1999-09-01), Danziger
patent: 5994339 (1999-11-01), Crapo et al.
patent: 5994410 (1999-11-01), Chiang et al.
patent: 6046188 (2000-04-01), Malfroy-Camine et al.
patent: 6084093 (2000-07-01), Riley et al.
patent: 6087493 (2000-07-01), Wheelhouse et al.
patent: 6103714 (2000-08-01), Fridovich et al.
patent: 6127356 (2000-10-01), Crapo et al.
patent: 6479477 (2002-11-01), Crapo et al.
patent: 6583132 (2003-06-01), Crapo et al.
patent: 6916799 (2005-07-01), Fridovich et al.
patent: 7470677 (2008-12-01), Crapo et al.
patent: 0 127 797 (1984-12-01), None
patent: 0 186 962 (1986-07-01), None
patent: 0 282 899 (1988-09-01), None
patent: 0 336 879 (1989-10-01), None
patent: 0 337 601 (1989-10-01), None
patent: 0 345 171 (1989-12-01), None
patent: 0 414 915 (1991-03-01), None
patent: 0 462 836 (1991-12-01), None
patent: 0 524 161 (1993-01-01), None
patent: 0 532 327 (1993-03-01), None
patent: 1616869 (2006-01-01), None
patent: 2 676 738 (1992-11-01), None
patent: WO 91/04315 (1991-04-01), None
patent: WO 92/07935 (1992-05-01), None
patent: WO 92/15099 (1992-09-01), None
patent: WO 94/04614 (1994-03-01), None
patent: WO 94/05285 (1994-03-01), None
patent: WO 95/10185 (1995-04-01), None
patent: WO 95/31197 (1995-11-01), None
patent: WO 96/09038 (1996-03-01), None
patent: WO 96/09053 (1996-03-01), None
patent: WO 96/40223 (1996-12-01), None
patent: WO 98/33503 (1998-08-01), None
patent: WO 99/23097 (1999-05-01), None
patent: WO 99/55388 (1999-11-01), None
patent: WO 00/43395 (2000-07-01), None
patent: WO 01/26655 (2001-04-01), None
patent: WO 01/96345 (2001-12-01), None
patent: WO 02/04454 (2002-01-01), None
patent: WO 02/096366 (2002-12-01), None
patent: WO 93/02090 (2007-11-01), None
Tjahjono et al., “Cationic porphyrins . . . ”, Biochmica et Biophysica Acta 1472 (1999) 333-343. Note: Closest prior art.
Office Action dated Sep. 4, 2009 in U.S. Appl. No. 11/857,949, 10 pages.
Archibald et al., Investigations of the State of the Manganese inLactobacillus plantarum, Archives of Biochemistry and Biophysics 215(2):589-596 (1982).
Archibald et al., Manganese and Defenses against Oxygen Toxicity inLactobacillus plantarum, Journal of Bacteriology 145(1):442-451 (1981).
Archibald et al., Manganese, Superoxide Dismutase, Oxygen Tolerance in Some Lactic Acid Bacteria, Journal of Bacteriology 146(3):928-936 (1981).
Archibald et al., The Scavenging of Superoxide Radical by Manganous Complex: In Vitro, Archives of Biochemistry and Biophysics 214(2):452-463 (1982).
Balch, “Geometric and electronic structure and dioxygen sensitivity of the copper complex of octaethylbilindione, a biliverdin analog”, J. Am. Chem. Soc. 115(25):12206-12207 (1993).
Balch, “Isolation and characterization of an iron biliverdin-type complex that is formed along with verdohemochrome during the coupled oxidation of iron (II) octaethylporphyrin”, Am. Chem. Soc. 115(20):9056-9061 (1993).
Balch, “Solid-state self-association of the two-electron oxidation product of a biliverdin analogue”, J. Chem. Soc. Chem. Commun. 6:643-644 (1995).
Bamford et al., “The Squalestatins: Synthesis and Biological Activity of Some C3-Modified Analogues; Replacement of a Carboxylic Acid or Methyl Ester with an Isoelectric Heterocyclic Functionality”, J. Med. Chem. 38:3502-3513 (1995).
Batinic-Haberle et al., “A Potent Superoxide Dismutase Mimic” Manganese[B]-Octabromo-meso-tetrakis (Nmethylpyridinium-4-yl)Porphyrin, Archives of Biochemistry and Biophysics 343(2):225-233 (1997).
Bockhorst and Hoehn-Berlage, “An Optimized Synthesis of Manganese meso-Tetra(4-sulfonato phenyl) porphine: A Tumor-Selective MRI Contrast Agent”, Tetrahedron 50(29):8657-8660 (1994).
Boissinot et al., “Rational Design and Expression of a Heparin-Targeted Human Superoxide Dismutase”, Biochemical and Biophysical Research Communication 190(1):250-256 (1993).
Bors et al., “An expanded function for superoxide dismutase”, Chemical Abstracts 115:388 (1991), Abstract No. 109185h.
Brigelius et al., “Superoxide Dismutase Activity of Low Molecular Weight Cu2+-Chelates Studied by Pulse Radiolysis”, FEBS Letters 47(1):72-75 (1974).
Burke, “Photochemical and thermal transformations of phytochrome”, Chem. Physiol. Bile Pigm., Int. Symp., pp. 509-517 (1975).
Butje et al., “Electronic Spectra, Resonance Raman Spectra and Solution Properties of Water-soluble (Cu(II), Ni(II) and Co(III) Porphyrins”, Inorg. Chim. Acta 167:97-108 (1990).
Callot and Schaeffer, “Ring contraction of homoporphyrins to porphyrins, meso-Reactivity of 5,10,15Triphenylporphin and Porphin”, J. Chem. Research (S):51 (1978).
Baudry et al., “Salen-Manganese Complexes are Superoxide Dismutase-Mimics”, Biochemical and Biophysical Research Communication 192(2):964-968 (1993).
Clyde et al., “Distribution of Manganese Superoxide Dismutase mRNA in Normal and Hyperoxic Rat Lung”, American Journal of Respiratory Cell and Molecular Biology 8:530-537 (1993).
Collman et al., “Synthesis of “Face to Face” Porphyrin Dimers Linked by 5,15-Substituents: Potential Binuclear Multielectron Redox Catalysts”, J. Am. Chem. Soc. 103:516-533 (1981).
Comhair et al., “Rapid loss of superoxide dismutase activity during antigen-induced asthmatic response”, Lancet 355 (9204):624 (2000).
Crapo and Tierney “Superoxide dismutase and pulmonary oxygen toxicity”, Am. J. Physiol. 226:1401-1407 (1974).
Crapo et al., “Superoxide Dismutase and Oxygen Toxicity”, Clinical Research, p. 222, 1991.
Crapo et al., “The Failure of Aerosolized Superoxide Dismutase to Modify Pulmonary Oxygen Toxicity”, American Review of Respiratory Disease 115:1027-1033 (1977).
Crapo et al., 721195, Document No. 123:218443 (1995).
Darr et al., “A Mimic of Superoxide Dismutase Activity Based Upon Desferrioxamine B and Manganese(IV)”, Archives of Biochemistry and Biophysics 258(2):351-355 (1987).
Datta-Gupta et al., “Synthetic Porphyrins II Preparation and Spectra of Some Metal Chelates of para”, Journal of Substituted-mesa-TetraDhenylporphines, J. of Pharmac

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Substituted porphyrins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted porphyrins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted porphyrins will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4177201

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.