Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-07-12
2005-07-12
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S184000, C514S185000, C540S145000
Reexamination Certificate
active
06916799
ABSTRACT:
The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
REFERENCES:
patent: 2951799 (1960-09-01), Sharp
patent: 4614723 (1986-09-01), Schmidt
patent: 4657902 (1987-04-01), Kappas et al.
patent: 4746735 (1988-05-01), Kruper, Jr. et al.
patent: 4758422 (1988-07-01), Quay
patent: 4829984 (1989-05-01), Gordon
patent: 4837221 (1989-06-01), Bonnett
patent: 4851403 (1989-07-01), Picker et al.
patent: 4866054 (1989-09-01), Dori et al.
patent: 4885114 (1989-12-01), Gordon et al.
patent: 4892941 (1990-01-01), Dolphin et al.
patent: 4895719 (1990-01-01), Radhakrishnam
patent: 4963367 (1990-10-01), Ecanow
patent: 5010073 (1991-04-01), Kappas et al.
patent: 5051337 (1991-09-01), Sakoda et al.
patent: 5087438 (1992-02-01), Gordon
patent: 5109016 (1992-04-01), Dixon et al.
patent: 5130245 (1992-07-01), Marklund et al.
patent: 5162519 (1992-11-01), Bonnett
patent: 5169630 (1992-12-01), Okaya et al.
patent: 5171680 (1992-12-01), Mullenbach et al.
patent: 5192757 (1993-03-01), Johnson et al.
patent: 5192788 (1993-03-01), Dixon et al.
patent: 5202317 (1993-04-01), Bruice
patent: 5217966 (1993-06-01), Bruice
patent: 5223538 (1993-06-01), Fridovich
patent: 5227405 (1993-07-01), Fridovich
patent: 5236914 (1993-08-01), Meunier
patent: 5236915 (1993-08-01), Fiel
patent: 5248603 (1993-09-01), Marklund et al.
patent: 5262532 (1993-11-01), Tweedle et al.
patent: 5277908 (1994-01-01), Beckman et al.
patent: 5281616 (1994-01-01), Dixon et al.
patent: 5284647 (1994-02-01), Niedballa
patent: 5366729 (1994-11-01), Marklund et al.
patent: 5403834 (1995-04-01), Malfroy-Camine et al.
patent: 5405369 (1995-04-01), Selman et al.
patent: 5472691 (1995-12-01), Marklund et al.
patent: 5493017 (1996-02-01), Therien et al.
patent: 5563132 (1996-10-01), Bodaness
patent: 5599924 (1997-02-01), Therien et al.
patent: 5604199 (1997-02-01), Funanage
patent: 5610293 (1997-03-01), Riley et al.
patent: 5637578 (1997-06-01), Riley et al.
patent: 5674467 (1997-10-01), Maier et al.
patent: 5747026 (1998-05-01), Crapo
patent: 5767272 (1998-06-01), Wijesekera et al.
patent: 5834509 (1998-11-01), Malfroy-Camine et al.
patent: 5874421 (1999-02-01), Riley et al.
patent: 5948771 (1999-09-01), Danziger
patent: 5976498 (1999-11-01), Neumann et al.
patent: 5976551 (1999-11-01), Mottez et al.
patent: 5994339 (1999-11-01), Crapo et al.
patent: 5994410 (1999-11-01), Chiang et al.
patent: 6013241 (2000-01-01), Marchal et al.
patent: 6046188 (2000-04-01), Malfroy-Camine et al.
patent: 6060467 (2000-05-01), Buelow et al.
patent: 6084093 (2000-07-01), Riley et al.
patent: 6087493 (2000-07-01), Wheelhouse et al.
patent: 6103714 (2000-08-01), Fridovich et al.
patent: 6127356 (2000-10-01), Crapo et al.
patent: 6180620 (2001-01-01), Salvemini
patent: 6204259 (2001-03-01), Riley et al.
patent: 6214817 (2001-04-01), Riley et al.
patent: 6245758 (2001-06-01), Stern et al.
patent: 6372727 (2002-04-01), Crow et al.
patent: 6395725 (2002-05-01), Salvemini
patent: 6403788 (2002-06-01), Meunier et al.
patent: 6417182 (2002-07-01), Abrams et al.
patent: 6544975 (2003-04-01), Crapo et al.
patent: 6548045 (2003-04-01), Sakata et al.
patent: 6566517 (2003-05-01), Miura et al.
patent: 6602998 (2003-08-01), Kobuke et al.
patent: 6624187 (2003-09-01), Pandey et al.
patent: 2002/0058643 (2002-05-01), Cherian et al.
patent: 0 127 797 (1984-12-01), None
patent: 0 186 962 (1986-07-01), None
patent: 0 282 899 (1988-09-01), None
patent: 0 336 879 (1989-10-01), None
patent: 0 337 601 (1989-10-01), None
patent: 0 345 171 (1989-12-01), None
patent: 0 414 915 (1991-03-01), None
patent: 0 462 836 (1991-12-01), None
patent: 0 524 161 (1993-01-01), None
patent: 0 532 327 (1993-03-01), None
patent: 2 676 738 (1992-11-01), None
patent: 91/04315 (1991-04-01), None
patent: WO 91/04315 (1991-04-01), None
patent: WO 91/19977 (1991-12-01), None
patent: 92/07935 (1992-05-01), None
patent: WO 92/08482 (1992-05-01), None
patent: WO 92/15099 (1992-09-01), None
patent: WO 93/02090 (1993-02-01), None
patent: WO 94/04614 (1994-03-01), None
patent: WO 94/05285 (1994-03-01), None
patent: WO 95/10185 (1995-04-01), None
patent: WO 95/31197 (1995-11-01), None
patent: WO 96/09038 (1996-03-01), None
patent: WO 96/09053 (1996-03-01), None
patent: WO 96/40223 (1996-12-01), None
patent: WO 97/06824 (1997-02-01), None
patent: WO 97/06830 (1997-02-01), None
patent: WO 97/06831 (1997-02-01), None
patent: WO 97/33588 (1997-09-01), None
patent: WO 97/33877 (1997-09-01), None
patent: WO 98/33503 (1998-06-01), None
patent: WO 98/58636 (1998-12-01), None
patent: WO 99/23097 (1999-05-01), None
patent: WO 99/55388 (1999-11-01), None
patent: WO 00/04868 (2000-02-01), None
patent: WO 00/43395 (2000-07-01), None
patent: WO 00/72893 (2000-12-01), None
patent: WO 01/26655 (2001-04-01), None
patent: WO 01/96345 (2001-12-01), None
Davila et al. {J. Chem. Soc. Chem. Commun., (1987), 525-527}.
Bütje et al. {Inorg. Chim. Acta, 167 (1990) 97-108}.
Sari et al. {Biochemistry, 29, (1990), 4205-4215}.
Comhair et al. (Medline abstract) and Rosenfeld et al. (Medline abstract).
Vodizinskii et al. (Russ. J. Org. Chem. 34(6) 1998, 882-885.
Kaufmann et al. {Inorg. Chem. 34, (1995), 5073}.
Hambright {J. Inorg. Nucl. Chem. 39, (1997), 1102}.
Hambright et al. {Porphyrin Chem. Adv., Pap. Porphyrin Symp. (1979), Meeting Date 1977, 284-92}.
Batinic-Haberle et al, “TheOrthoEffect Makes Manganese(III) Meso-Tetrakis-(N-Methylpyridinium-2-yl)Porphyrin a Powerful and Potentially Useful Superoxide Dismutase Mimic”, The Journal of Biological Chemistry 273(38):24521-24528 (1998).
Inoue et al, “Expression of a Hybrid Cu/Zn-type Superoxide . . . ” J. Bio. Chem., vol. 266. No. 25. pp. 16409-16414 (1991).
Day et al. “Manganic Porphyrins Possess Catalase Activity . . . ,” Arch. Biochem. Biophys., vol. 347. No. 2. pp. 256-262 (1997).
Tsan. M-F., “Superoxide Dismutase and Pulmonary Oxygen Toxicity.” XP-002074505, pp. 286-290.
Naruta et al. (1991) J. Am. Chem. Soc. 113:3595-3596.
Leondiadis et al. (1989) J. Org. Chem. 54:6135-6138.
Foran et al. “Effect of Electrolyte Concentration on Axial Anion Ligation in Manganese(III) meso-Tetraphenylporphyrin Chlorides”. Inorg. Chem. 31:1463-1470 (1992).
Milgrom, Facile Aenal Oxidation of a Porphyrin. Part 3. Some Metal Complexes of meso-Tetrakis-(3,5-di-t-butyl-4-hydroxyphenyl)porphyrin. J. Chem. Soc. Perkin Trans. 11:71-79 (1988).
Bockhorst and Hoehn-Bertage, “An Optimized Synthesis of Manganese mesoTetra(4-sulfonato-phenyl)porphine: A Tumor-Selective MRI Contrast Agent”, Tetrahedron 50(29):8657-8660 (1994).
Keinan et al, “Catalytic Antibodies. Circular Dichroism and UV-Vis Studies of Antibody-Metalloporphyrin Interactions”. Inorg. Chem. 31:5433-5438 (1992).
Marx, “Role of Gene Defect in Heredity ALS Clarified”, Science 261:986 (1993).
Epp et al, “Superoxide Dismutase Activity of Manganese Chelates”, 76-78 (1986).
Bors et al, “An expanded function for superoxide dismutase”, Chemical Abstracts 115:388 (1991), Abstract No. 109185h.
Miigrom et al, “Redox Behaviour of Phenolic Porphyrins in Basic Solutions: A Reappraisal”, Free Rad. Res. 24(1):19-29 (1996).
Szabo et al, “Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger”, FEBS Letters 381:82-86 (1996).
Patel et al, “Requirement for Superoxide in Excitotoxic Cell Death”, Neuron 16:345-355 (1996).
Bamford et al, “The Squalestatins: Synthesis and Biological Activity of Some C3-Modified Analogues; Replacement of a Carboxylic Acid or Methyl Ester with an Isoelectric Heterocyclic Functionality”, J. Med. Che
Batinic-Haberle Ines
Crapo James D.
Day Brian J.
Fridovich Irwin
Duke University
National Jewish Medical and Research Center
Nixon & Vanderhye P.C.
Wilson James O.
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