Substituted piperidines, pharmaceutical compositions...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S500000

Reexamination Certificate

active

07026312

ABSTRACT:
The present invention relates to substituted piperidines of general formulawherein R, R2to R5, A, X, Z and n are defined as in claim 1, the tautomers, diastereomers, enantiomers, mixtures and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases which have valuable pharmacological properties, particularly CGRP-antagonistic properties, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof.

REFERENCES:
patent: 6344449 (2002-02-01), Klaus et al.
patent: 6521609 (2003-02-01), Doods et al.
patent: WO-981128 (1998-03-01), None
Thurieau et al. “Preparation of imidazolyl . . . ” CA 132:35701 (1999).

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