Substituted piperidines, medicaments containing these...

Details Substituted piperidines, medicaments containing these... Substituted piperidines, medicaments containing these...

2005-09-27

2005-09-27

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S221000, C514S266210, C514S266220, C514S253010, C540S495000, C540S500000, C544S286000, C544S360000, C544S364000

Reexamination Certificate

active

06949541

ABSTRACT:
The present invention relates to substituted piperidines of general formulawhereinA1, A2, R, R1and R2are defined as in claim 1, the tautomers, the diastereomers, the enantiomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable pharmacological properties, particularly CGRP-antagonistic properties, pharmaceutical compositions containing these compounds, their use and processes for preparing them.

REFERENCES:
patent: 196 36 623 (1998-03-01), None
patent: WO 98 11128 (1998-03-01), None
patent: WO 00 18764 (2000-04-01), None
Doods, H. et al; “Pharmacological Profile of BIBN4096BX, The First Selective Small Molecule CGRP Antagonist”, British Journal of Pharmacology, Basingstoke, Hants; Bd. 129, Nr. 3, 2000 420-423 CA 128:230701.

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