Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-04-19
1996-03-19
Rizzo, Nicholas
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142288, 544295, 544369, 544370, A61K 31495, A61K 31535, C07D40304, C07D41304
Patent
active
055004261
ABSTRACT:
A compound selected from those of formula (I): ##STR1## in which A represents ##STR2## X represents N--R.sub.4 or oxygen, and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, n and m are as defined in the description,
useful in improving glucose tolerance in the treatment of non-insulin-dependent diabetes.
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Nathani, P., Indian Journal of Chemistry, "2,3-Disubstituted Quinazolinones and Their Antiparkinsonian Activity", vol. 28B (1989) pp. 745-750 Month of Publication not Provided.
Street, L., J. Med. Chem., "Synthesis and Biological Activity of 1,2,4-Oxadiazo Derivatives: Highly Potent and Efficacious Agonists for Cortical Muscarinic Receptors", 33, (1990), 2690-2697 Month of Publication not Provided.
Kuzmierkiewicz, W., Scientia Pharmaceutica, "3,5-Disubstituted Derivatives of 1,2,4-Triazole Synthesis and Hypotensive Activity", 53, (1985) 133-138 Month of Publication not Provided.
Godfroid Jean-Jacques
Guardiola Beatrice
Lamouri Aazdine
Pfeiffer Bruno
Renard Pierre
Adir et Compagnie
Hueschen Gordon W.
Rizzo Nicholas
Wong King L.
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