Substituted piperazines as central nervous system agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514252, 544295, 544357, 544360, 544363, 544364, A61K 31495, C07D40300, C07D40100, C07D24102

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active

050894978

ABSTRACT:
Substituted piperazines and derivatives thereof are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as dopaminergic, antipsychotic, and antihypertensive agents as well as for treating hyperprolactinaemia-related conditions and central nervous system disorders.

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J. R. Boissier et al., CA63-15381g (1965).
Societe Industrielle pour la Fabrication des Antibiotques, CA59-2832e.
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Chemical Pharmaceutical Bulletin, vol. 26, pp. 3296-3305 (1978) M. Sato, et al.
JP 4804478 (62436U-B) Daiichi Seiyaku Co. Ltd.
Boll. Chem. Farm. vol. 119, pp. 608-618 (1980), C. Bacciarelli et al.

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