Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-04-30
1997-09-30
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514254, 514255, 544373, 544384, 544392, 544393, 544394, 544399, 544400, 544402, A61K 31495, C07D40306, C07D40304, C07D24104
Patent
active
056726023
ABSTRACT:
The present invention relates to substituted piperazine derivatives (herein referred to as compounds or compounds of formula (1)) or stereoisomers, or pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, cough, and bronchitis.
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Burkholder Timothy P.
Kudlacz Elizabeth M.
Le Tieu-Binh
Bernhardt Emily
Collier Kenneth J.
Hoechst Marion Roussel Inc.
Stemerick David M.
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