Substituted phthalide derivatives

Details Substituted phthalide derivatives Substituted phthalide derivatives

1978-10-10

1980-02-12

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260325PH, 424279, C07D30788

Patent

active

041883306

ABSTRACT:
Method of preparing chlorthalidone, an antihypertensive agent, and derivatives using a novel 3-(4'-chloro-3'-chlorosulfonylphenyl)phthalide intermediate and derivatives, and method of preparing said novel intermediate, are disclosed.

REFERENCES:
patent: 3055904 (1962-09-01), Graf et al.
patent: 3296276 (1967-01-01), Sherlock et al.
Graf et al. (II), Helv. Chim. Acta., XLII, p. 1085, 1959.
Graf et al. Chem. Abstracts, vol. 62, 16200c, vol. 58, 9028d, vol. 59, 9901e, vol. 58, 11330h.

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