Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-06-28
1986-12-23
Marantz, Sidney
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544360, A61K 31445, C07D40110
Patent
active
046312811
ABSTRACT:
Substituted phenylpiperazinyl-propanols of the formula I ##STR1## in which R.sup.1 denotes hydrogen or an alkyl group with 1 to 4 carbon atoms and R.sup.2 and R.sup.3, which can be identical or different, each denote hydrogen, halogen, cyano, a trifluoromethyl group, a nitro group, a hydroxyl group, an alkoxy group or an alkyl group with in each case 1 to 4 carbon atoms, it being possible for the alkyl parts in each case to be straight-chain or branched, and their tautomeric forms and their salts as well as acid addition salts and N-oxides, have useful pharmacological properties, in particular a positively inotropic, vasodilating, broncholytic and platelet aggregation-inhibiting action and are therefore suitable for the treatment of cardiac insufficiency, hypertension, asthma and thrombosis.
REFERENCES:
patent: 3941789 (1976-03-01), Renth
Journal of Medicinal Chemistry, 1974, vol. 17, No. 5, pp. 529-533.
Hofferber Eva
Stenzel Wolfgang
Beiersdorf Aktiengesellschaft
Benson Robert
Marantz Sidney
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