Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1978-05-12
1981-10-06
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
2603976, 260455A, 560 9, 560 13, C07C15502, C07C149437, C07C14714, A61K 31325
Patent
active
042935695
ABSTRACT:
Phenylguanidine derivatives are provided having the structure ##STR1## wherein R is hydrogen, lower alkyl, cycloalkyl, lower alkoxy, phenyl, phenylalkyl, phenoxy, phenylalkoxy, lower alkoxyalkyl, phenoxyalkyl, alkylamino, dialkylaminoalkyl, alkylthio, phenylthio, phenylthioalkyl, and alkylthioalkyl; R.sup.1 is lower alkyl or benzyl; R.sup.2 is hydrogen, lower alkoxy carbonyl, and lower alkanoyl; R.sup.3 is lower alkyl, cycloalkylalkyl, lower alkenyl, lower alkynyl or benzyl; and n is 0 or 1. These compounds are useful as anthelmintic agents.
REFERENCES:
patent: 3828094 (1974-08-01), Widdig
patent: 3993682 (1976-11-01), Kollig
patent: 4024176 (1977-05-01), Kollig
patent: 4032655 (1977-06-01), Kollig
patent: 4246260 (1981-01-01), Kolling
Lowy, "Introduction to Organic Chemistry," 7th Ed., p. 215 (1951).
Haugwitz Rudiger D.
Maurer Barbara V.
Wade Peter C.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Rodney Burton
Shippen Michael
Trousof Natalie
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