Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-11-06
1994-02-22
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C07D30736, C07D33322, A61K 3134, A61K 3138
Patent
active
052887510
ABSTRACT:
The present invention relates to compounds of the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein Z is selected from optionally substituted phenyl, furyl, thienyl or thiazolyl; which inhibits leukotriene biosynthesis and is useful in the treatment of inflammatory disease states; also disclosed are leukotriene biosynthesis inhibiting compositions and a method for inhibiting 5-lipoxygenase activity and leukotriene biosynthesis.
Basha Anwer
Bhatia Pramila
Brooks Dee W.
Ratajczyk James D.
Stewart Andrew O.
Abbott Laboratories
Janssen Jerry F.
Rotman Alan L.
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