Substituted phenoxyhydroxypropyl amines as central nervous syste

Details Substituted phenoxyhydroxypropyl amines as central nervous syste Substituted phenoxyhydroxypropyl amines as central nervous syste

1994-10-11

1996-01-09

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514650, 514652, 514653, 564338, 564341, 564349, 564351, A61K 31135, C07C21760, C07C32332, C07C32338

Patent

active

054829640

ABSTRACT:
Substituted phenoxyhydroxy amines and derivatives thereof are described as well as methods for the preparation and pharmaceutical compositions of same, which are central nervous system agents useful in the treatment of neurological disorders including traumatic brain surgery, stroke, migraine, acute and chronic pain, epilepsy, Parkinson's disease, Alzheimer's disease, amyotropic lateral sclerosis, multiple sclerosis, psychosis, and depression.

REFERENCES:
patent: 3857891 (1974-12-01), Holmes et al.
patent: 5382689 (1995-01-01), Nomura
Miyano et al, J. Org. Chem., vol. 50 (1985) pp. 4350-4360.
Runge et al, Chemical Abstracts, vol. 87 (1977) 134458k.

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