Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Reexamination Certificate
2007-06-05
2007-06-05
Zucker, Paul A. (Department: 1621)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
C560S075000
Reexamination Certificate
active
10928801
ABSTRACT:
The invention provides substituted phenol compounds and pharmaceutical compositions containing substituted phenol compounds which are useful for inducing or maintaining anesthesia or sedation in a mammal. This invention also provides methods for inducing or maintaining anesthesia or sedation in a mammal using substituted phenol compounds.
REFERENCES:
patent: 3029276 (1962-04-01), Hausweiler et al.
patent: 3112338 (1963-11-01), Smutny et al.
patent: 3642868 (1972-02-01), Dexter et al.
patent: 3790648 (1974-02-01), Schmidt et al.
patent: 3808296 (1974-04-01), Brunetti et al.
patent: 3887638 (1975-06-01), Crescentini et al.
patent: 4228235 (1980-10-01), Okonogi et al.
patent: 5155122 (1992-10-01), Connor et al.
patent: 5395752 (1995-03-01), Law et al.
patent: 5510361 (1996-04-01), Scherz et al.
patent: 5879894 (1999-03-01), Law et al.
patent: 5908869 (1999-06-01), Jones et al.
patent: 6204257 (2001-03-01), Stella et al.
patent: 6815555 (2004-11-01), Jenkins et al.
patent: 0 636 647 (1995-02-01), None
patent: 1 324 055 (1973-07-01), None
patent: 59 072443 (1984-04-01), None
patent: 61 020856 (1986-01-01), None
patent: 61 218558 (1986-09-01), None
patent: WO 99/58555 (1999-11-01), None
patent: WO 00/07972 (2000-02-01), None
patent: WO 00/48572 (2000-08-01), None
patent: WO 01/26656 (2001-04-01), None
Clarke, “The Eugenols”, Intravenous Anaesthesia, Chapter 8, pp. 162-192 (1974).
Cooke et al., “Water-Soluble Propofol Analogues with Intravenous Anaesthetic Activity”, Bioorganic & Medicinal Chemistry Letters, 11:927-930 (2001).
James et al., “Synthesis, Biological Evaluation, and Preliminary Structure-Activity Considerations of a Series of Alkylphenols as Intravenous Anesthetic Agents”, J. Med. Chem., 23:1350-1357 (1980).
Krasowski et al., “General Anesthetic Potencies of a Series of Propfol Analogs Correlate with Potency for Potentiation of γ-Aminobutyric Acid (GABA) Current at the GABAAReceptor but Not with Lipid Solubility”, J. of Pharmacology and Experimental Therapeutics, 297:338-351 (2001).
Trapani et al., “Propofol Analogues, Synthesis, Relationships between Structure and Affinity at GABAAReceptor in Rat Brain, and Differential Electrophysiological Profile at Recombinant Human GABAAReceptors”, J.Med. Chem., vol. 41, pp. 1846-1854 (1998).
Bolton Jennifer
Jenkins Thomas E.
Ji Yu-Hua
Wu Huiwei
Hagenah Jeffrey A.
Saxon Roberta P.
Theravance Inc.
Zucker Paul A.
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