Substituted pentaalkylchromans

Details Substituted pentaalkylchromans Substituted pentaalkylchromans

1993-03-05

1994-05-17

Cintins, Marianne M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

C07C 3919

Patent

active

053130073

ABSTRACT:
The substituted pentaalkylchromans of the general formula: ##STR1## wherein R denotes a lower alkyl group having 1 to 4 C atoms and Hal denotes chlorine, bromine or iodine, are novel intermediates for the preparation of hypolipidaemic pharmaceuticals. A process for their preparation is described in which a trialkylhydroquinone is reacted with a halogenated butenol to give a substituted tetraalkylhydroquinone, which is finally cyclized to the final product.

REFERENCES:
patent: 5135945 (1992-08-01), Robinson et al.
J. Med. Chem., 32, (1989), pp. 421 to 428.

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