Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2003-07-25
2009-11-03
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S362000
Reexamination Certificate
active
07612075
ABSTRACT:
This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa.
REFERENCES:
patent: 3935214 (1976-01-01), Zellner
patent: 5559232 (1996-09-01), Ackermann et al.
patent: 5612353 (1997-03-01), Ewing et al.
patent: 5798352 (1998-08-01), Danilewicz
patent: 5877174 (1999-03-01), Ono et al.
patent: 6093718 (2000-07-01), Waterson et al.
patent: 6300330 (2001-10-01), Sticker et al.
patent: 6335341 (2002-01-01), Johnson et al.
patent: 6359134 (2002-03-01), Tawada et al.
patent: 6369063 (2002-04-01), Su et al.
patent: 6403595 (2002-06-01), Tawada et al.
patent: 6525042 (2003-02-01), Kobayashi et al.
patent: 0365992 (1990-05-01), None
patent: 0783500 (1998-07-01), None
patent: 1048652 (2000-11-01), None
patent: 1054005 (2000-11-01), None
patent: WO 96/10022 (1996-04-01), None
patent: WO 97/06802 (1997-02-01), None
patent: WO 97/28129 (1997-08-01), None
patent: WO 97/29104 (1997-08-01), None
patent: WO 97/38984 (1997-10-01), None
patent: WO 98/09987 (1998-03-01), None
patent: WO 98/21188 (1998-05-01), None
patent: WO 98/46591 (1998-10-01), None
patent: WO 98/46626 (1998-10-01), None
patent: WO 98/46627 (1998-10-01), None
patent: WO 98/46628 (1998-10-01), None
patent: WO 98/54164 (1998-12-01), None
patent: WO 99/06371 (1999-02-01), None
patent: WO 99/06395 (1999-02-01), None
patent: WO 99/09027 (1999-02-01), None
patent: WO 99/46267 (1999-09-01), None
Abad-Zapatero, et al., Structure of a Secreted Aspartic Protease From Candida Albicans Complexed with a Potent Inhibitor: Implications for the Design Of Antifungal Agents, Chemical Abstract, 124:311048, XP-002195405, RN 176200-48-9, Protein Sci (1996) 5(4) 640-52.
Struve, et al., Syntheses Of And Structural Assignments For Some N-Phosphono-2-iminoimidazolidines (Cyclic Guanidines), J. Org. Chem., vol. 42, No. 25, 1977 (4035-4040).
Yamawaki, et al., 1-Halophenyl-4-acyl-2-piperazinones, Chemical Abstract, 82:171054, XP002195404, JP 49 110680, Oct. 22, 1974.
1-Cyclohexyl-4-p-tolylsulfonyl-2-Piperazin one, Database Crossfire Beilstein, 565750, XP002195407, Collect. Czech. Chem. Commun. (1960), 25, 2651-2661.
4-(4-Methylphenyl) Sulfonyl I-1-Phenyl-2,6-Piperazinedione, Database Crossfire Beilstein, 838927, XP002195406, Nippon Kagaku Kaishi (1978), (12), 1661-5.
Tawada, et al. et al., Preparation of Sulfonamides As Inhibitors of Blood Coagulation Factor X, Chemical Abstract, vol. 131:170361, 1999.
Becker Michael R.
Bobko Mark A.
Burns Christopher J.
Choi-Sledeski Yong Mi
Condon Stephen M.
Aventis Pharmaceuticals Inc.
Lin Jiang
Ort Ronald G.
Sackey Ebenezer
Wilson James O.
LandOfFree
Substituted oxoazaheterocyclyl compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted oxoazaheterocyclyl compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted oxoazaheterocyclyl compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4103354