Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-10-31
2009-08-18
Anderson, Rebecca L (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S231000
Reexamination Certificate
active
07576111
ABSTRACT:
The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I)processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
REFERENCES:
patent: 2811555 (1957-10-01), Larive et al.
patent: 3279880 (1966-10-01), Straley et al.
patent: 4128654 (1978-12-01), Fugitt et al.
patent: 4250318 (1981-02-01), Dostert et al.
patent: 4327725 (1982-05-01), Cortese et al.
patent: 4500519 (1985-02-01), Lormeau et al.
patent: 4705779 (1987-11-01), Madi-Szabo et al.
patent: 4765989 (1988-08-01), Wong et al.
patent: 5002937 (1991-03-01), Bosies et al.
patent: 5254577 (1993-10-01), Carlson et al.
patent: 5349045 (1994-09-01), Jiang
patent: 5532255 (1996-07-01), Raddatz et al.
patent: 5561148 (1996-10-01), Gante et al.
patent: 5565571 (1996-10-01), Barbachyn et al.
patent: 5654428 (1997-08-01), Barbachyn et al.
patent: 5654435 (1997-08-01), Barbachyn et al.
patent: 5688792 (1997-11-01), Barbachyn et al.
patent: 5756732 (1998-05-01), Barbachyn et al.
patent: 5792765 (1998-08-01), Riedl et al.
patent: 5801246 (1998-09-01), Barbachyn et al.
patent: 5827857 (1998-10-01), Riedl et al.
patent: 5910504 (1999-06-01), Hutchinson et al.
patent: 5922708 (1999-07-01), Riedl et al.
patent: 5929248 (1999-07-01), Barbachyn et al.
patent: 5972947 (1999-10-01), Tsaklakidis et al.
patent: 6069160 (2000-05-01), Stolle et al.
patent: 6251869 (2001-06-01), Bohanon
patent: 6273913 (2001-08-01), Wright et al.
patent: 6294201 (2001-09-01), Kettelhoit et al.
patent: 6413981 (2002-07-01), Paget et al.
patent: 6610682 (2003-08-01), Tsujita et al.
patent: 6805881 (2004-10-01), Kanikanti et al.
patent: 6818243 (2004-11-01), Nagashima et al.
patent: 7034017 (2006-04-01), Straub et al.
patent: 7045631 (2006-05-01), Rosentreter et al.
patent: 7078417 (2006-07-01), Rosentreter et al.
patent: 7109218 (2006-09-01), Rosentreter et al.
patent: 7129255 (2006-10-01), Rosentreter et al.
patent: 7157456 (2007-01-01), Straub et al.
patent: 7351823 (2008-04-01), Berwe et al.
patent: 2001/0029351 (2001-10-01), Falotico et al.
patent: 2003/0153610 (2003-08-01), Straub et al.
patent: 2003/0161882 (2003-08-01), Waterman
patent: 2004/0162427 (2004-08-01), Rosentreter et al.
patent: 2004/0242660 (2004-12-01), Straub et al.
patent: 2005/0064006 (2005-03-01), Perzborn et al.
patent: 2005/0182055 (2005-08-01), Berwe et al.
patent: 2005/0261502 (2005-11-01), Rosentreter et al.
patent: 2006/0154969 (2006-07-01), Rosentreter et al.
patent: 2006/0258724 (2006-11-01), Straub et al.
patent: 2007/0026065 (2007-02-01), Benke et al.
patent: 2007/0149522 (2007-06-01), Thomas
patent: 2008/0026057 (2008-01-01), Benke
patent: 2008/0090815 (2008-04-01), Straub et al.
patent: 2008/0200650 (2008-08-01), Straub et al.
patent: 2008/0200674 (2008-08-01), Straub et al.
patent: 744002 (1999-07-01), None
patent: 2 437 587 (2002-08-01), None
patent: 2 451 258 (2003-01-01), None
patent: 2 464 290 (2003-05-01), None
patent: 2836305 (1979-03-01), None
patent: 196 04 223 (1997-08-01), None
patent: 19962924 (2001-07-01), None
patent: 10105989 (2002-08-01), None
patent: 10129725 (2003-01-01), None
patent: 10355461 (2005-06-01), None
patent: 0 127 902 (1984-12-01), None
patent: 0 316 594 (1989-05-01), None
patent: 0 352 781 (1990-01-01), None
patent: 0350002 (1990-01-01), None
patent: 0 623 615 (1994-11-01), None
patent: 0645376 (1995-03-01), None
patent: 0 738 726 (1996-10-01), None
patent: 0 785 200 (1997-07-01), None
patent: 0930076 (1999-07-01), None
patent: 0950386 (1999-10-01), None
patent: 2140687 (1984-12-01), None
patent: WO-93/09103 (1993-05-01), None
patent: WO-93/23384 (1993-11-01), None
patent: WO-97/03072 (1997-01-01), None
patent: WO-97/09328 (1997-03-01), None
patent: WO-97/10223 (1997-03-01), None
patent: WO-98/01446 (1998-01-01), None
patent: WO-98/54161 (1998-12-01), None
patent: WO-99/02525 (1999-01-01), None
patent: WO-99/03846 (1999-01-01), None
patent: WO-99/06371 (1999-02-01), None
patent: WO-99/21535 (1999-05-01), None
patent: WO-99/24428 (1999-05-01), None
patent: WO-99/29688 (1999-06-01), None
patent: WO-99/29688 (1999-06-01), None
patent: WO-99/31092 (1999-06-01), None
patent: WO-99/37304 (1999-07-01), None
patent: WO-99/37630 (1999-07-01), None
patent: WO-99/37641 (1999-07-01), None
patent: WO-99/40094 (1999-08-01), None
patent: WO-99/59616 (1999-11-01), None
patent: WO-00/16748 (2000-03-01), None
patent: WO-01/42242 (2001-06-01), None
patent: WO-01/44212 (2001-06-01), None
patent: WO-01/46185 (2001-06-01), None
patent: WO-01/47919 (2001-07-01), None
patent: WO-01/47949 (2001-07-01), None
patent: WO-02/25210 (2002-03-01), None
patent: WO-02/064575 (2002-08-01), None
patent: WO-02/064575 (2002-08-01), None
patent: WO-02/070484 (2002-09-01), None
patent: WO-02/070520 (2002-09-01), None
patent: WO-92/070485 (2002-09-01), None
patent: WO-02/079195 (2002-10-01), None
patent: WO-02/079196 (2002-10-01), None
patent: WO-03/000256 (2003-01-01), None
patent: WO-03/008384 (2003-01-01), None
patent: WO-03/035133 (2003-05-01), None
patent: WO-03/035133 (2003-05-01), None
patent: WO-03/053441 (2003-07-01), None
patent: WO-2004/060887 (2004-07-01), None
patent: WO-2005/060940 (2005-05-01), None
patent: WO-2005/068456 (2005-07-01), None
patent: WO-2006/072367 (2006-07-01), None
patent: WO-2006/079474 (2006-08-01), None
patent: WO-2007/036306 (2007-04-01), None
patent: WO-2007/039122 (2007-04-01), None
patent: WO-2007/039132 (2007-04-01), None
patent: WO-2007/039134 (2007-04-01), None
patent: WO-2007/042146 (2007-04-01), None
patent: WO-2008/012002 (2008-01-01), None
patent: WO-2008/052671 (2008-05-01), None
Riedl, B., Endermann, “Recent Developments with Oxazolidinone Antibiotics,” R., Exp. Opin. Ther. Patents 1999, 9 (5), 625-633.
Barbachyn, M.R. et al., “Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity,” J. Med. Chem. 1996, 39, 680-685.
Tucker, J.A. et al, “Piperazinyl Oxazolidinone Antibacterial Agents Containing a Pyridine, Diazene, or Triazene Heteroaromatic Ring,” J. Med. Chem. 1998, 41, 3727-3735.
Brickner, S.J. et al., “Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections,” J. Med. Chem. 1996, 39, 673.
Gregory, W.A. et al., “Antibacterials. Synthesis and Structure-Activity Studies of 3-Aryl-2-oxooxazolidines. 1. The “B” Group,” J. Med. Chem. 1989, 32, 1673-1681.
Berry, C.N. et al., “Antithrombotic Actions of Argatroban in Rat Models of Venous, ‘Mixed ’ and Arterial Thrombosis and its Effects on the Tail Transection Bleeding Time,” Br. J. Pharmacol. 1994, 113, 1209-1214.
Meng, K. et al., “Effect of Acetylsalicylic Acid on Experimentally Induced Arterial Thrombosis in Rats,” Naunyn-Schmiedeberg's Arch. Pharmacol. 1977, 301, 115-119.
Chern, J.W. et al., “Studies on Quinazolines IX: Fluorination versus 1,2-Migration in the Reaction of 1,3-Bifunctionalized amino-2-propanol with DAST,” Tetrahedron Lett. 1998, 39, 8483-8486.
Shakespeare, W.C., “Palladium-Catalyzed Coupling of Lactones with Bromobenzenes,” Tetrahedron Lett. 1999, 40, 2035-2038.
Renger, “Direct N-Arylation of Amides: An Improvement of the Goldberg-Reaction,” Synthesis Sep. 1985, 856-860.
Aebischer et al., “Synthesis of N-Arylrolipram Derivatives—Potent and Selective Phosphodiesterase-IV Inhibitors—By Copper Catlyzed Lactam-Aryl Halide Coupling,” Heterocycles. 1998, 48, 2225-2229.
Pfeil, E. et al., “Synthese von Oxalactamen aus Aziridinium-tetrafluoroborat und Hydroxysäureestern,” Agnew Chem. 79, 1967, 188.
Ziegler, C.B., et al., “Synthesis of Some Novel 7-Subsituted Quinolonecarboxylic Acids via Nitroso and Nitrone Cycloadditions,” J. Hetercycl. Chem. 25, 2, 1988, 719-723.
Bartoli et al, “Electronic and Steric Effects in Nucleophilic Aromatic Substitution. Reactio
Lampe Thomas
Pernerstorfer Joseph
Perzborn Elisabeth
Pohlmann Jens
Rohrig Susanne
Anderson Rebecca L
Bayer Schering Pharma AG
Connolly Bove & Lodge & Hutz LLP
LandOfFree
Substituted oxazolidinones and their use in the field of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted oxazolidinones and their use in the field of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted oxazolidinones and their use in the field of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4097172