Substituted oxazolidinones and their use in the field of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S137000, C548S229000

Reexamination Certificate

active

07034017

ABSTRACT:
This invention relates to compounds of formula (I)wherein R1represents optionally substituted phenyl, R2represents optionally substitutedand the remaining “R” groups are as defined in the specification and claims, as well as a method for making such materials, pharmaceutical compositions containing such materials, and methods of using such materials in medical treatment.

REFERENCES:
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patent: 9906371 (1999-11-01), None
patent: 0147919 (2001-07-01), None
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Hauptmann, et al., “Synthetic Inhibitors of Thrombin and Factor Xa: From Bench to Bedside,” Thrombosis Res. 93, 203-241, (1999).
Al-Obeidi, et al., “Factor Xa Inhibitors by Classical and Combinatorial Chemistry”, DDT, 3, 223-231, (1998).
Zhu, et al., “Recent Advances in Inhibitors of Factor Xa in the Prothrombinase Complex”, Curr. Opin. in Cardiovas. Pul. & Renal Investigational Drugs, 1, 63-88, (1999).
Al-Obeidi, et al., “Factor Xa Inhibitors”, Exp. Opin. Ther. Patents 9, 931-953, (1999).
Kaiser, “Thrombin snd Factor Xa Inhibitors,” Drugs of the Future, 23, 423-436, (1998).
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