Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-12-18
2008-09-30
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S266200, C514S266400, C544S284000, C544S293000
Reexamination Certificate
active
07429597
ABSTRACT:
The present invention relates to new substituted nitrogen-containing heterobicyclic compounds of general formulawherein B, X1to X3and R1to R5are defined as in claim1,the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties.The compounds of the above general formula I as well as the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, and their stereoisomers have valuable pharmacological properties, particularly an antithrombotic activity and a factor Xa-inhibiting activity.
REFERENCES:
patent: 5693652 (1997-12-01), Takase et al.
patent: 6046206 (2000-04-01), Pamukcu et al.
patent: 6087380 (2000-07-01), Hauel et al.
patent: 6414008 (2002-07-01), Hauel et al.
patent: 6469039 (2002-10-01), Hauel et al.
patent: 6710055 (2004-03-01), Hauel et al.
patent: 2 277 949 (1998-08-01), None
patent: WO 97/03069 (1997-01-01), None
patent: WO 98/37075 (1998-08-01), None
International Search Report for PCT/EP03/14378 mailed May 10, 2004.
Flavia Messina, et al; Stereoselective Synthesis of α-aryl-2-Benzofuranmethanamines and α-aryl-1 H-indole-2-methanamines Through Pallladium-Mediated Annulation of Chiral α-arylpropargylamines; Tetrahedron Asymmetry (2000) vol. 11 pp. 1681-1685.
R. Marshall Wilson, et al; Synthesis and Chemistry of a Stabilized Dehydrosecodine Model System; Journal of Organic Chemistry (1981) vol. 46 pp. 3293-3302.
Bauer Eckhart
Gerlach Kai
Nar Herbert
Pfau Roland
Priepke Henning
Boehringer Ingelheim Pharma GmbH & Co. KG
Devlin Mary-Ellen M.
Lebel Edouard G.
Morris Michael P.
Truong Tamthom N
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