Substituted N-phenylpiperidines and drugs therefrom

Details Substituted N-phenylpiperidines and drugs therefrom Substituted N-phenylpiperidines and drugs therefrom

1992-03-11

1994-03-22

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514183, 514255, 514307, 514317, 514318, 544 1, 544360, 546150, 546191, 546194, 546217, 546223, 546229, 546237, A61K 31445, C07D40104, C07D21700

Patent

active

052964850

ABSTRACT:
Substituted N-phenylpiperidines I ##STR1## (R.sup.1 =H, NO.sub.2, CN, halogen, C.sub.1 -C.sub.4 -alkyl, CF.sub.3, OCF.sub.3, OH, CH.sub.2 OH, COOH, CHO, NH--CHO, NH.sub.2, CO--NH.sub.2, 5-tetrazinyl, R.sup.4 --O--, R.sup.4 --O--CH.sub.2 --, R.sup.4 O--CO--, R.sup.4 --CO--, R.sup.4 --NH--CO, R.sup.4 --CO--NH--, R.sup.4 --SO.sub.2 --NH--;

REFERENCES:
patent: 3468892 (1969-09-01), Tomchecik
patent: 4603138 (1986-07-01), Maschler
patent: 4603138 (1986-07-01), Maschler
patent: 4902800 (1990-02-01), Skotnieki
patent: 5071859 (1991-12-01), Knudsen
Pang K. S. "Drug Absorption, Distribution and Elimination" p. 89 (1990).
Chem. Ber. 74 (1941) 1648, 1658 and 1661.
Helv. Chim. Acta 26 (1943) 1132.

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