Substituted N-(imidazolyl)alkyl alanine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514269, 514341, 514365, 514374, 514376, 514381, 514383, 514384, 514398, 514400, 544333, 546278, 548112, 548171, 548252, 5482644, 5483151, 5483164, 5483211, 5483225, 5483235, 5483241, 5483255, 5483285, 5483355, A61K 31415, C07D25702, C07D23330, C07D23342

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active

052486893

ABSTRACT:
Angiotensin II receptor antagonists having the formula: ##STR1## which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mammals.

REFERENCES:
patent: 4340598 (1982-07-01), Furukawa et al.
patent: 4355040 (1982-10-01), Furukawa et al.
Burger, A. Medicinal Chemistry, 2nd Ed., New York, pp. 565-571, 578-581, 600-601, (1960).
Denkewalter et al., Progress in Drug Research, vol. 10, pp. 510-512, (1966).

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