Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-10-15
2000-07-18
Woodward, Michael P.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 18, 530331, 562560, 562575, A61K 3805
Patent
active
060907851
ABSTRACT:
Novel N-carboxyalkylpeptidyl compounds represented by the formula ##STR1## which are found to be useful inhibitors of matrix metalloendoproteinases which degrade major components of articular cartilage and basement membranes causing degenerative diseases such as arthritis, periodontal disease, corneal ulceration and the like, and certain cancers, are described.
REFERENCES:
patent: 4511504 (1985-04-01), McCullugh et al.
patent: 4568666 (1986-02-01), McCullugh et al.
patent: 4771037 (1988-09-01), Roberts et al.
patent: 4935404 (1990-06-01), Hunter et al.
patent: 4937243 (1990-06-01), Markwell et al.
patent: 5672583 (1997-09-01), Chapman
patent: 5932551 (1999-08-01), Caldwell
Durette Philippe L.
Esser Craig K.
Hagmann William K.
Kopka Ihor E.
Lukton David
McGinnis James L.
Merck & Co. , Inc.
Rose David L.
Woodward Michael P.
LandOfFree
Substituted N-carboxyalkylpeptidyl derivatives as antidegenerati does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted N-carboxyalkylpeptidyl derivatives as antidegenerati, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted N-carboxyalkylpeptidyl derivatives as antidegenerati will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2037163