Substituted N-arylpyrrolidines as selective androgen...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S577000

Reexamination Certificate

active

07807691

ABSTRACT:
The present invention provides a compound of the Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising an effective amount of a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly frailty, osteoporosis, osteopenia, and male and female sexual dysfunction comprising administering to a patient in need thereof an effective amount of a compound of Formula (I).

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patent: WO 01/27107 (2001-04-01), None
patent: WO 2004/016576 (2004-02-01), None
patent: WO 2005/000795 (2005-01-01), None
RN 860759-80-4, retrieved from CAPLUS on Jun. 10, 2009.
Tucker, et al., “Nonsteroidal Antiandrogens. Synthesis and Structure-Activity Relationships of 3-Substituted Derivatives of 2-Hydroxypropionanilides,”Journal of Medicinal Chemistry, American Chemical Society. Washington, US, vol. 31, No. 5, pp. 954-959 (1988).
Elslager, et al., “Folate Antagonists. 3. 2,4-Diamino-6-(Heterocyclic)Quinazolines, a Novel Class of Antimetabolites with Potent Antimalarial and Antibacterial Activity,”Journal of Medicinal Chemistry, American Chemical Society. Washington, US, vol. 15, No. 8, pp. 827-836 (1972).

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