Substituted n-aryl amidines as selective D 1 dopamine...

Details Substituted n-aryl amidines as selective D 1 dopamine... Substituted n-aryl amidines as selective D 1 dopamine...

2004-12-21

2008-09-09

Wilson, James (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C546S184000, C564S244000

Reexamination Certificate

active

07423149

ABSTRACT:
The present invention provides compounds, which, are novel antagonists for D1receptors as well as methods for preparing such compounds. In another embodiment, the invention provides pharmaceutical compositions comprising such D1receptor antagonists as well as methods of using them to treat CNS disorders, obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.

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Robeff, St. Doklady Bolgarskoi Akademii Nauk (1955), Volume Date 1954, 7(No. 3), 37-40. (based on CAPlus record).
Robev . Doklady Bolgarskoi Akademii Nauk (1968), 21(11), 1181-3. (based on CAPlus record).
Okubo et al. Journal of Physical Organic Chemistry, 1993, 6(9), 509-19. (based on CAPlus record).
Borisy et al. Proceedings of the National Academy of Sciences, 2004, 100(13), 7977-82.

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