Substituted n-aryl-1,2-diaminocyclobutene-3,4-diones

Details Substituted n-aryl-1,2-diaminocyclobutene-3,4-diones Substituted n-aryl-1,2-diaminocyclobutene-3,4-diones

1994-11-04

1995-11-14

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

5483381, 5483401, 558413, 558414, 558415, 564 84, 564 90, 564 92, 564 99, 564180, 564184, 564207, 564218, 514400, 514602, 514604, 514605, 514617, 514625, 514627, 514629, 514646, C07C22508, A61K 31275, A61K 31135

Patent

active

054667127

ABSTRACT:
The compound of the formula (I) or a pharmaceutically acceptable salt thereof, are smooth muscle relaxants ##STR1##

REFERENCES:
patent: 4390701 (1983-06-01), Algieri et al.
patent: 4673747 (1987-06-01), Nohara et al.
Tietze, et al., Squaric Acid Diethyl Ester: A New Coupling Reagent for the Formation of Drug Biopolymer Conjugates. Synthesis of Squaric Acid Ester Amides and Diamides, Chem. Ber., 124, p. 1215, 1991.
Tietze, et al., Conjugation of p-Aminophenyl Glycosides with Squaric Acid Diester to a Carrier Protein and the Use of Neoglycoprotein in the Histochemical Detection of Lectins, Bioconjugate Chem., 2, p. 148, 1991.
Ehrhardt, et al., Amide und Thioamide der Quadratsaure: Synthese und Reaktionen, Chem. Ber., 110, p. 2506, 1977.
Neuse, et al., Amidierung von Quadratsaure-estern, Liebigs Ann. Chem., p. 619, 1973.

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