Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl am

Details Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl am Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl am

1997-06-27

2000-06-27

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514538, 514563, 514617, 544353, 544365, 546111, 546121, 546169, 546194, 546278, 546280, 546281, 546284, 546332, 548128, 548204, 548255, 5483094, 5483361, 5483741, 549366, 549441, 560 35, 560251, 562440, 564157, 564161, C07C25718, A61K 31216

Patent

active

060807679

ABSTRACT:
The compounds according to the invention are substituted N-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides of formula I herein which exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More especially, they are Factor Xa inhibitors. The present invention is directed to compounds of formula I, compositions containing compounds of formula I, methods for their preparation and their use, which are for treating a patient suffering from, or subject to, conditions which can be ameliorated by the administration of an inhibitor of Factor Xa.

REFERENCES:
patent: 5424334 (1995-06-01), Abood

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