Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-01-07
1997-03-25
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5142382, 514255, 514428, 544160, 544398, 546232, 548569, 564 89, A61K 31445, A61K 3140, A61K 31495, A61K 31535
Patent
active
056145365
ABSTRACT:
Substituted N-aminoalkylmethane sulfanilide of formula (I), their solutions and pharmaceutically acceptable addition salts, their pharmaceutical compositions and their therapeutic use. In formula (I) Y represents hydrogen, cyano, nitro, amino, acetamide or halogen; n is an integer between 2 and 4, R.sup.1 and R.sup.2 equal or different are alkyl-(C1-C4) or they are connected together and with the N-atom thereby forming a 1-pyrrolidinyl, 1-piperidinyl, 1-piperazinyl, 4-methyl-1-piperazinyl, 4-ethylpiperazinyl, 4-propylpiperazinyl, 1-homopiperidinyl or 4-morpholine residue. The products of formula (I) are used as antispasmodic agents. ##STR1##
REFERENCES:
patent: 3531522 (1970-09-01), Nelson
patent: 3840597 (1974-10-01), Moore
patent: 3876651 (1975-04-01), Subirana
patent: 4055650 (1977-10-01), Dlarge
Morrison & Boyd, Organic Chemistry, 2d. ed., Allyn & Bacon, Boston, pp. 334-335 (1966).
Chemical Abstracts, 107: 70814v (2).
Aldom a Gustavo E.
Monti Carlos E. A.
Chang Ceila
Roemmers S.A.I.C.F.
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