Substituted monocyclic aryl compounds exhibiting selective leuko

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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514562, 514381, 514538, 514539, 562442, 562426, 562443, 562451, 560 42, 560 37, 548253, 548251, A61K 3119, C07C22934

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active

052329488

ABSTRACT:
Monocyclic aryl compounds having selective LTB.sub.4 antagonists properties and comprising an amido substituent, a substituent group having a terminal carboxylic acid or derivative thereof and a lipophilic substituent, therapeutic compositions and methods of treatment of disorders which result from LTB.sub.4 activity using the monocyclic aryl compounds are disclosed.

REFERENCES:
patent: 3828095 (1974-08-01), Boschetti
patent: 4460580 (1984-07-01), Ostermayer et al.
patent: 4497813 (1985-02-01), Ostermayer et al.
F. Ostermayer et al. (IV), Chemical Abstracts 93:P220465r, p. 502, (1980) English abstract of E.P. patent 5,848.
F. Ostermayer et al. (III), Chemical Abstracts 94:121135x, p. 660 (1981) English abstract of E.P. patent 15,505.

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