Substituted metal-phthalocyanines, their preparation and the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S191000, C514S163000, C514S410000, C540S128000, C540S123000, C540S140000, C540S125000, C536S029110

Reexamination Certificate

active

07144879

ABSTRACT:
The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization

REFERENCES:
patent: 0 906 758 (1999-04-01), None
patent: 0906758 (1999-04-01), None
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Brasseur et al., “Biological Activities of Phthalocyanines—IX. Photosensitization of V-79 Chinese Hamster Cells and EMT-6 Mouse Mammary Tumor by Selectively Sulfonated Zinc Phthalocyanines,”Photochem. Photobiol., 47(5):705-711 (1988).
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Gaspard, “A New Method for the Synthesis of Zinc Tetrakis-(3-methylpyridyloxy)-phthalocyanine and the Physical Properties of—Dimers Formed by Complexation of the Cationic Phthalocyanine with Anionic Porphyrins,”J. Chem. Soc. Perkin Trans. II, 383-389 (1989).
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Kaninskii et al., “Substitution of the Nitro Group in 4-Nitrophthalonitrile with the Phenol-Metal Carbonate System as Nucleophile,”Journal of Organic Chemistry of the USSR, 38:964-967 (1992).
Mikhalenko et al., “Phthalocyanines and Related Compounds. XIX. Tetra- and Octaamino-Substituted Phthalocyanines,”Journal of Chemistry, 51(7):1405-1411 (1981).
Haworth et al., “Some Green Pigments of the Phthalocyanine Series,”Chemical Abstracts, 39(20), Abstract No. 4610 (1945).
Freccero et al., “Photochemical Reaction of Phthalimides and Dicyanophtalimides with Benzylic Donors,”J. Org. Chem., 58:1740-1745 (1993).
Gracheva et al., “Preparation of 1,2,3,4-tetrahydroquinoline Derivatives,” Caplus Online Chemical Abstracts Service, Abstract No. 108:204512 (1987).

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