Substituted lactams and their use as anti-cancer agents

Details Substituted lactams and their use as anti-cancer agents Substituted lactams and their use as anti-cancer agents

2008-05-27

2008-05-27

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S526000, C540S527000

Reexamination Certificate

active

10565700

ABSTRACT:
This invention relates to certain substituted lactam compounds of the formula (I), particularly caprolactam compounds, which are useful for the treatment of cancer

REFERENCES:
patent: WO00/29382 (2000-05-01), None
patent: WO01/85697 (2001-11-01), None
patent: WO02/39990 (2002-05-01), None
Boeckman, Robert et al., “Synthesis of bengamides via polyol intermediate”, Helvetica Chimica Acta, vol. 85, pp. 4532-4560, 2002.
Kinder, Frederick et al., “Synthesis and antitumour activity of ester modified analogues of bengamide B”, J. Med. Chem, vol. 44, pp. 3692-3699, 2001.

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