Substituted indolizine-like compounds and methods of use

Details Substituted indolizine-like compounds and methods of use Substituted indolizine-like compounds and methods of use

2005-07-26

2005-07-26

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252160, C514S259100, C514S259500, C544S263000, C544S281000

Reexamination Certificate

active

06921762

ABSTRACT:
Selected novel substituted indolizine-like compounds are effective for treatment of diseases, such as TNF-α, IL-1β, IL-6 and/or IL-8 mediated diseases, and other maladies, such as cancer, pain and diabetes. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for treatment of diseases and other maladies or conditions involving inflammation, cancer, pain, diabetes and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

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