Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-02-22
2005-02-22
Jones, Dwayne C. (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S418000, C548S484000, C548S486000
Reexamination Certificate
active
06858641
ABSTRACT:
The present invention relates to indolinones substituted in the 6-position of general formulawhereinR1to R5and X are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof which have valuable pharmacological properties, in particular an inhibiting effect on various receptor tyrosine kinases and cyclin/CDK complexes and on the proliferation of endothelial cells and various, pharmaceutical compositions containing these compounds, their use and processes for preparing them.
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Roth, G. J. et al, U.S. Appl. No. 10/069,557, filed Jul. 22, 2002, “New Substituted Indolinones, Their Manufacture and Their Use As Medicaments”.
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Heckel Armin
Hilberg Frank
Kley Joerg
Lehmann-Lintz Thorsten
Roth Gerald Juergen
Boehringer Ingelheim Pharma KG
Datlow Philip I.
Jones Dwayne C.
Morris Michael P.
Raymond Robert P.
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